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S0B1300Rat Anti-Mouse CD186 antibody (S-R602)

產(chǎn)品型號:S0B1300
更新時間:2025-10-08
廠商性質(zhì):生產(chǎn)廠家
訪問量:98
服務(wù)熱線15855403091
產(chǎn)品分類
CD186, also known as CXCR6, is a G protein-coupled chemokine receptor with seven transmembrane domains. It is expressed on activated and memory T cells and its ligand is the chemokine CXCL16. CXCR6 plays a role in the recruitment of cells to inflamed sites and is also a coreceptor for HIV-1 and SIV to enter target cells, in conjunction with CD4. This receptor is involved in the regulation of T lymphocyte migration to various peripheral tissues and promotes cell-cell interaction with dendritic cells and fibroblastic reticular cells. Additionally, CXCR6/CCL16 controls the localization of resident memory T lymphocytes to different compartments of the lung and maintains airway resident memory T lymphocytes, which are crucial for defense against respiratory pathogens.
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