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產(chǎn)品中心抗體/抗原流式抗體S0B5019Armenian hamster Anti-Mouse/Human Helios Antibody (S-R640)
產(chǎn)品型號(hào)：S0B5019
更新時(shí)間：2025-10-08
廠商性質(zhì)：生產(chǎn)廠家
訪問量：143
服務(wù)熱線15855403091
產(chǎn)品分類
Helios protein （encoded by the IKZF2 gene） is a member of the Ikaros family of transcription factors and contains multiple zinc finger domains that facilitate DNA binding and the formation of homodimers or heterodimers. It is predominantly expressed in T cells, regulatory T cells （Tregs）, certain B cell subsets, and hematopoietic and epithelial tissues. Helios plays a crucial role in T cell activation, proliferation, and the stability and function of Tregs. Additionally, Helios has been identified as a potential biomarker in autoimmune diseases and may influence tumor development by regulating gene expression and modulating cell differentiation and proliferation.
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