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S0B5196APC Mouse Anti-Human CD134 Antibody (S-R589)

產(chǎn)品型號:S0B5196
更新時間:2025-10-08
廠商性質(zhì):生產(chǎn)廠家
訪問量:100
服務(wù)熱線15855403091
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CD134, also known as OX40 or TNFRSF4, is a co-stimulatory molecule belonging to the tumor necrosis factor receptor superfamily. It is primarily expressed on activated CD4+ and CD8+ T cells, as well as other immune cells like natural killer (NK) cells and dendritic cells. CD134 plays a crucial role in enhancing T-cell proliferation, cytokine production, and survival by interacting with its ligand, CD134L (OX40L), which is mainly expressed on antigen-presenting cells (APCs) such as dendritic cells and macrophages. This interaction promotes T-cell-mediated immune responses and helps maintain memory T cells, making CD134 an important target for immunotherapy. In cancer treatment, agonistic antibodies targeting CD134 have been shown to enhance anti-tumor immunity by boosting T-cell activity and overcoming immune suppression.
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