Rat Anti-Mouse CD5 Antibody (S-R732)

Name: Rat Anti-Mouse CD5 Antibody (S-R732)S0B5234
Brand: Starter/斯達特
Price: 600 CNY
Availability: InStock

產(chǎn)品型號：S0B5234

更新時間：2025-10-08

廠商性質(zhì)：生產(chǎn)廠家

訪問量：107

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抗體/抗原

ELISA試劑盒抗體試劑盒二抗試劑盒二抗其它流式抗體瓊脂糖/磁珠偶聯(lián)抗體抗Payload抗體泛修飾抗體標簽/內(nèi)參抗體功能性抗體 Biosimilar抗體偶聯(lián)抗體配對抗體病理/IHC抗體

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產(chǎn)品介紹

CD5, also known as T-cell surface glycoprotein CD5 or Leu-1, is a type I transmembrane glycoprotein expressed on the surface of T cells, thymocytes, and a subset of B cells called B-1a cells. It belongs to the scavenger receptor superfamily and has a molecular mass of approximately 67 kDa. CD5 plays a crucial role in modulating immune responses by regulating the activation of T cells and B cells. In T cells, CD5 expression is upregulated upon activation and helps to fine-tune T cell receptor （TCR） signaling, promoting cell survival and non-responsiveness. In B cells, particularly B-1a cells, CD5 helps to prevent overactivation by dampening signals from the B cell receptor （BCR）, ensuring that these cells only respond to strong stimuli. The exact ligand for CD5 remains unclear, but it is suggested that it may interact homophilically or with CD72 on B cells.

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