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S0B2105PTEN Recombinant Rabbit mAb (SDT-R074)

產(chǎn)品型號:S0B2105
更新時間:2025-10-09
廠商性質(zhì):生產(chǎn)廠家
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服務(wù)熱線15855403091
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PTEN is a dual-specificity phosphatase at two levels. First, PTEN has been shown to dephosphorylate protein substrates on serine/threonine and tyrosine residues, thus acting as a dual-specificity protein phosphatase. One example is the tyrosine dephosphorylation of focal adhesion kinase (FAK) to inhibit cell spreading. Second, PTEN also dephosphorylates phosphatidylinositol 3,4,5-trisphosphate (PIP3) to phosphatidylinositol 4,5-bisphosphate (PIP2) — hence, PTEN is also a dual-specificity phosphatase in the sense that it dephosphorylates lipid substrates in addition to protein substrates.
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