S-RMab? p53 Recombinant Rabbit mAb (SDT-R118)

Name: S-RMab? p53 Recombinant Rabbit mAb (SDT-R118)S0B2146
Brand: Starter/斯達(dá)特
Price: 600 CNY
Availability: InStock

產(chǎn)品型號(hào)：S0B2146

更新時(shí)間：2025-10-09

廠商性質(zhì)：生產(chǎn)廠家

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產(chǎn)品介紹

P53 is a gene that encodes for the p53 tumor suppressor protein, commonly referred to as the “Guardian of the Genome" [PMID: 1614522

IF: 50.5 Q1 B1].The p53 protein is a transcription factor that controls the output of many biological processes according to the type of cellular stress signal input. Stress signals known to activate p53 include oncogene activation, DNA damage, and replication stress [PMID: 28886379

IF: 45.5 Q1 B1]. In response to these stresses, p53 undergoes post-translational modifications, promotes the transcription of genes involved in specific cell responses according to the stress type thereby controlling the cell’s fate [PMID: 15510160

IF: 72.5 Q1 B1]. When the p53 protein is mutated or aggregated, it loses its function, resulting in tumor progression and growth [PMID: 29789497

IF: 4.5 Q1 B2].