13774214275
13774214275
產(chǎn)品中心
當前位置：首頁
產(chǎn)品中心抗體/抗原偶聯(lián)抗體S0B1837CD8α Mouse mAb (Alexa Fluor? 594 Conjugate) (SDT-1036-34)
產(chǎn)品型號：S0B1837
更新時間：2025-10-11
廠商性質(zhì)：生產(chǎn)廠家
訪問量：247
服務熱線15855403091
產(chǎn)品分類
CD8α is a crucial subunit of the CD8 co-receptor complex found on the surface of cytotoxic T lymphocytes （CTLs） and some natural killer （NK） cells. It is a 32 kDa glycoprotein that can form either an α/β heterodimer or an α/α homodimer with CD8β. CD8α plays a vital role in immune responses by binding to MHC class I molecules on antigen-presenting cells （APCs）, facilitating the recognition and destruction of infected or abnormal cells. This interaction helps activate the T cell receptor （TCR） complex, recruiting the LCK kinase and initiating multiple signaling pathways. Additionally, CD8αα homodimers are found on intraepithelial lymphocytes （IELs）, which protect mucosal surfaces like the intestinal barrier.
上一個：
返回列表
