PE-Cy7 Rat Anti-Mouse CD8α Antibody (S-R540)

Name: PE-Cy7 Rat Anti-Mouse CD8α Antibody (S-R540)S0B5159
Brand: Starter/斯達(dá)特
Price: 975 CNY
Availability: InStock

產(chǎn)品型號(hào)：S0B5159

更新時(shí)間：2025-10-08

廠商性質(zhì)：生產(chǎn)廠家

訪問量：147

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ELISA試劑盒抗體試劑盒二抗試劑盒二抗其它流式抗體瓊脂糖/磁珠偶聯(lián)抗體抗Payload抗體泛修飾抗體標(biāo)簽/內(nèi)參抗體功能性抗體 Biosimilar抗體偶聯(lián)抗體配對(duì)抗體病理/IHC抗體

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產(chǎn)品介紹

CD8α is a crucial immune glycoprotein that plays a vital role in the immune system as a co-receptor for the T-cell receptor （TCR） on T cells. It is typically found in a heterodimer with CD8β or as a homodimer in certain cell types. CD8α binds to MHC class I molecules on antigen-presenting cells （APCs） to facilitate the recognition of intracellular pathogens, such as viruses and cancer cells, by cytotoxic T lymphocytes （CTLs）. This interaction is essential for T cell activation and the initiation of downstream signaling pathways, including the recruitment of LCK kinase. Additionally, CD8α is expressed on intraepithelial lymphocytes （IELs） in the gut, where it contributes to mucosal immunity and the maintenance of gut barrier integrity.

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