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產(chǎn)品中心抗體/抗原流式抗體S0B5336Alexa Fluor? 647 Mouse Anti-Human CD41a Antibody (S-R554)
產(chǎn)品型號：S0B5336
更新時間：2025-10-09
廠商性質：生產(chǎn)廠家
訪問量：102
服務熱線15855403091
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相關文章
CD41, also known as Integrin α-IIb or GPαIIb, is a protein expressed on platelets and megakaryocytes. CD41 is a component of the platelet membrane glycoprotein complex and non-covalently associates with CD61 （Integrin β-3） to form the αIIbβ3 complex, which is an essential integrin in platelets. It plays a crucial role in platelet activation and aggregation, particularly during thrombus formation and hemostasis. In clinical practice, the detection of CD41 is essential for diagnosing and studying platelet-related diseases. For instance, immunostaining for CD41 can help identify micromegakaryocytes, which might be confused with primitive megakaryocytes or lymphocytes in Wright-Giemsa staining, leading to missed diagnoses. CD41 staining can significantly improve the detection rate of micromegakaryocytes, which is crucial for the diagnosis and therapeutic monitoring of certain hematological disorders.
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