FITC Rat Anti-Mouse CD155 Antibody (S-R720)

Name: FITC Rat Anti-Mouse CD155 Antibody (S-R720)S0B5404
Brand: Starter/斯達(dá)特
Price: 1051 CNY
Availability: InStock

產(chǎn)品型號：S0B5404

更新時間：2025-10-09

廠商性質(zhì)：生產(chǎn)廠家

訪問量：124

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ELISA試劑盒抗體試劑盒二抗試劑盒二抗其它流式抗體瓊脂糖/磁珠偶聯(lián)抗體抗Payload抗體泛修飾抗體標(biāo)簽/內(nèi)參抗體功能性抗體 Biosimilar抗體偶聯(lián)抗體配對抗體病理/IHC抗體

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產(chǎn)品介紹

CD155, also known as Poliovirus Receptor （PVR） or Necl-5, is a type I transmembrane glycoprotein belonging to the nectin and nectin-like protein family. It is widely expressed in various tissues and is involved in multiple cellular processes. Structurally, CD155 consists of three extracellular immunoglobulin-like domains （D1-D3）, with D1 being the domain recognized by the poliovirus. This protein plays a crucial role in the establishment of intercellular adherens junctions between epithelial cells. In the context of cancer, CD155 is often overexpressed in tumor cells, where it promotes cell proliferation, adhesion, invasion, and migration. Additionally, CD155 interacts with several immune receptors, such as DNAM-1 （CD226）, TIGIT, and CD96, to modulate immune responses. These interactions can either enhance antitumor immunity or contribute to immune evasion, depending on the specific receptor involved. Due to its complex roles in tumor progression and immune regulation, CD155 has emerged as a promising target for cancer immunotherapy.

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